TOXIC EFFECTS OF POTENTIAL AGENTS FOR BORNEUTRON CAPTURE THERAPY

  • O. Makeev Ural State Medical University
  • O. Gubina Ural State Medical University
  • A. Korotkov Ural State Medical University
  • E. Yakovleva Ural State Medical University
  • L. Galliamova Ural Federal University
Keywords: boron neutron capture therapy, cell line

Abstract

The aim of the investigation was to study the cytotoxicity of boron-containing compounds intended for boron neutron capture therapy of oncopathology. The studies were performed on human cell cultures.

The results obtained indicate a low toxic effect of the GL-57 sample as compared to the GL-63 sample.

Author Biographies

O. Makeev , Ural State Medical University

Professor, Doctor of Medical Sciences

Head of the Department of Medical Biology and Genetics  of Ural State Medical University

Head of the Laboratory of Gene and Cellular Technologies  of Institute of Medical Cell Technology

O. Gubina , Ural State Medical University

Trainee researcher

A. Korotkov , Ural State Medical University

Candidate of Medical Sciences, 

Associate Professor of the Department of Medical Biology and Genetics 

E. Yakovleva , Ural State Medical University

Trainee researcher

L. Galliamova, Ural Federal University

PhD in Chemistry

Senior Researcher

References

1. Makeev OG, Ulybin AI, Zubanov PS Patent No. 2345781 "Method for obtaining a culture of skin cells" // Bulletin of inventions No. 4, 10.02.2009.
2. Freshny R.Ya. Animal cell culture. Practical guide; per. 5th English edition. - M .: BINOM. Knowledge Laboratory, 2010 .-- 691 p.
3. Kroemer G. Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009 // Cell.Death.Diff. Vol.16- P.3-11.
Published
2020-12-14
How to Cite
(1)
Makeev , O.; Gubina , O.; Korotkov , A.; Yakovleva , E.; Galliamova, L. TOXIC EFFECTS OF POTENTIAL AGENTS FOR BORNEUTRON CAPTURE THERAPY . Eurasian Union of Scientists 2020, 3, 20-22.

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