TOXIC EFFECTS OF POTENTIAL AGENTS FOR BORNEUTRON CAPTURE THERAPY

  • O. Makeev Ural State Medical University
  • O. Gubina Ural State Medical University
  • A. Korotkov Ural State Medical University
  • E. Yakovleva Ural State Medical University
  • L. Galliamova Ural Federal University
DOI: https://doi.org/10.31618/ESU.2413-9335.2020.3.80.1107
Keywords: boron neutron capture therapy, cell line

Abstract

The aim of the investigation was to study the cytotoxicity of boron-containing compounds intended for boron neutron capture therapy of oncopathology. The studies were performed on human cell cultures.

The results obtained indicate a low toxic effect of the GL-57 sample as compared to the GL-63 sample.

Author Biographies

O. Makeev , Ural State Medical University

Professor, Doctor of Medical Sciences

Head of the Department of Medical Biology and Genetics  of Ural State Medical University

Head of the Laboratory of Gene and Cellular Technologies  of Institute of Medical Cell Technology

O. Gubina , Ural State Medical University

Trainee researcher

A. Korotkov , Ural State Medical University

Candidate of Medical Sciences, 

Associate Professor of the Department of Medical Biology and Genetics 

E. Yakovleva , Ural State Medical University

Trainee researcher

L. Galliamova, Ural Federal University

PhD in Chemistry

Senior Researcher

References

Makeev OG, Ulybin AI, Zubanov PS Patent No. 2345781 "Method for obtaining a culture of skin cells" // Bulletin of inventions No. 4, 10.02.2009.

Freshny R.Ya. Animal cell culture. Practical guide; per. 5th English edition. - M .: BINOM. Knowledge Laboratory, 2010 .-- 691 p.

Kroemer G. Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009 // Cell.Death.Diff. Vol.16- P.3-11.

Published
2020-12-14
How to Cite
Makeev , O., O. Gubina, A. Korotkov, E. Yakovleva, and L. Galliamova. 2020. “TOXIC EFFECTS OF POTENTIAL AGENTS FOR BORNEUTRON CAPTURE THERAPY ”. EurasianUnionScientists 3 (11(80), 20-22. https://doi.org/10.31618/ESU.2413-9335.2020.3.80.1107.
Issue
Vol. 3 No. 11(80) (2020): EURASIAN UNION OF SCIENTISTS №80
Section
Article

CC BY-ND

A work licensed in this way allows the following:

1. The freedom to use and perform the work: The licensee must be allowed to make any use, private or public, of the work.

2. The freedom to study the work and apply the information: The licensee must be allowed to examine the work and to use the knowledge gained from the work in any way. The license may not, for example, restrict "reverse engineering."

2. The freedom to redistribute copies: Copies may be sold, swapped or given away for free, in the same form as the original.