THE USE OF MESENCHIMAL STEM CELLS TO STIMULATE THE REGENERATION OF SPINAL CORD TISSUES IN EXPERIMENTAL CONTUSION TRAUMA IN PIGS

  • D. Amirov Kazan State Academy of Veterinary Medicine named after N.E. Bauman
  • M. Sergeev Kazan State Academy of Veterinary Medicine named after N.E. Bauman
Keywords: pigs, spinal cord injury, neurological examination, stem cells, myelography, liquor

Abstract

As a result of a modulated spinal cord contusion injury, the pigs in the acute post-traumatic period showed symptoms of spinal shock, which manifested as Schiff-Shirington syndrome and the absence of autonomic spinal reflexes.

More complete elimination of functional neurological dysfunction after spinal cord injury was observed in animals that were applied to the area of the damaged segment of the spinal cord with mesenchymal stem cells (MSCs) of adipogenic origin.

Author Biographies

D. Amirov , Kazan State Academy of Veterinary Medicine named after N.E. Bauman

Candidate of Science, assistant professor

M. Sergeev , Kazan State Academy of Veterinary Medicine named after N.E. Bauman

Candidate of Science, assistant professor

References

1.Федеральный закон от 14.05.1993 N 4979-1 (ред. от 13.07.2015) «О ветеринарии». [Электронный источник] - URL: https://lpvetst.ru/normativnye-dokumenty/federalnoezakonodatelstvo-/4979-1.pdf / (дата обращения 10.12.2020).
2.Применение аллогенного остеопластического материала «Лиопласт» и аллогенных мезенхимальных стволовых клеток в ветеринарной травматологии / Е.Ю. Закирова, [и др.] // Актуальные вопросы ветеринарной биологии.- СПб.: «Институт ветеринарной биологии», 2017. - Т.33(1). - С.46-52.
3.Лисяный, Н.И. Мезенхимальные стволовые клетки и канцерогенез / Н.И. Лисяный // Онкология. - 2013. - Т. 15(1). - С. 4-8.
4.A novel porcine model of traumatic thoracic spinal cord injury / Lee, J. H. T. [et al] // Neurotrauma. - 2013. - V. 30(3). - P.142-159.
5.Genetic modification of mesenchymal stem cells in spinalcord injury repair strategies / Cui, X. [et al] // Bioscience Trends. - 2013. - V. 7(5). - P.202-208.
Published
2021-01-18
How to Cite
Amirov , D., and M. Sergeev. 2021. “THE USE OF MESENCHIMAL STEM CELLS TO STIMULATE THE REGENERATION OF SPINAL CORD TISSUES IN EXPERIMENTAL CONTUSION TRAUMA IN PIGS ”. EurasianUnionScientists 2 (12(81), 25-29. https://archive.euroasia-science.ru/index.php/Euroasia/article/view/338.
Issue
Vol. 2 No. 12(81) (2020): EURASIAN UNION OF SCIENTISTS №81
Section
Article

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