EFFECT OF EPIPHYSIS ON REGULATION OF THE FUNCTIONAL STATE OF THE BLOOD COLLECTION AND FIBRINOLYSIS SYSTEM DURING THE DAY
Abstract
Purpose to investigate the role of the epiphysis in the regulation of blood aggregate state – we studied changes in blood clotting time, the content and activity of certain hemocoagulation factors in intact and epiphysectomized animals during the day
Method. In animals, the epiphysis was removed by a modified method of D. M. Aulov (1969). Influence of the epiphysis on the regulation of the functional state of the blood clotting system and fibrinolysis during the day – at 9, 12, 14, 18 hours. Blood clotting time was determined by the method of Lee and Uifyt, plasma tolerance to heparin by Sigg, recaltification time by Howell, thrombin time and free heparin by Sirmai, activity of prothrombin complex factors by Quick, platelet count by Danilin, fibrinogen and fibrinolytic activity by Kuznik.
28 Евразийский Союз Ученых (ЕСУ) #9(78), 2020
Result. The epiphysis is actively involved in the chain of neurohormonal regulation of the functional blood clotting system
Conclusions. The data of our research quite convincingly show that the epiphysis is actively involved in the chain of neurohormonal regulation of the blood clotting system in General, in the regulation of the daily rhythm, in particular. The epiphysis is included in a single mechanism of the epiphyseal-hypothalamic-pituitary-adrenal
system.
References
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